The global Fragment Based Drug Discovery market is expected to grow from USD 0.516 billion in 2019 to USD 1.23 billion by 2027, at a CARG of 12.1% during the forecast period 2020-2027.
Fragment-based drug discovery (FBDD) also known as Fragment-based lead discovery, a powerful approach for discovering drugs leads, is a measure for developing and identifying new drugs for various disease. It’s a key approach for discovering high-quality lead candidates. FBDD has a good record of success even for the difficult targets, in which other methods failed. FBDD process begins by identifying small molecules which are about half size of typical drug molecule. And then, the fragments are improved and interacted together to develop drug leads. The greater the molecule, the more complex it gets, as there are more chances of interactions with a protein target. And a small fragment forms less interactions with protein target. The FBDD method is gradually used in pharmaceutical industries, for decreasing attrition and giving leads for previously intractable biological targets. This market dominates the biopharmaceutical companies, as it need a system that helps in discovering lead compounds during the process of drug discovery.
The market of fragment-based drug discovery is increasing and is expected to grow in the coming years. The rising exploration of new drugs for treatment of major medical problems is the leading factor for the increased demand for fragment-based drug discovery market. The new technology and techniques have also helped this market to grow significantly over the years. The introduction of new techniques has significantly reduced time and cost which drives demand for these practices.
The study delivers a comprehensive analysis by type, application and region. The type segment includes Fragment Screening, Fragment Optimization. The Fragment screening is sub-segmented into biophysical techniques and non-biophysical techniques. The biophysical technique includes, DSF assay, Surface Plasmon Resonance, Fluorescence Polarization (FP), NMR Spectroscopy, X-ray Crystallography, Isothermal Titration Calorimetry, Mass Spectrometry and other. NMR Spectroscopy is highly efficient and productive because of recent modifications, and X-ray crystallography gives a detail profile of fragment-binding. Identifying crystal structures with x-ray crystallography has become a high-throughput process. Fragment-based screening has appeared as a promising tool in drug discovery process. The application segment includes Academic and Research Institutions, Biopharmaceutical Companies, Contract Research Organization.
The regional segment of this market includes Europe, Middle East & Africa, North America, South America and Asia-Pacific. North America is dominating the market of fragment-based drug discovery. This is due to, high investment by the players in R&D of drug discovery, developed and advanced healthcare systems and infrastructure and technology advancement.
The key players of Fragment-based Drug Discovery market are, Evotec AG, Charles River Laboratories International, Crown Bioscience, Astex Pharmaceuticals, Sprint Bioscience, Kinetic Discovery Limited, Alveus Pharmaceuticals Pvt. Ltd.
Global Fragment-based drug discovery Market Analysis and Forecast, By Type
Global Fragment-based drug discovery Market Analysis and Forecast, By Application
Global Fragment-based drug discovery Market Analysis and Forecast, By Regional Analysis
1. Introduction
1.1. Objectives of the Study
1.2. Market Definition
1.3. Research Scope
1.4. Currency
1.5. Key Target Audience
2. Research Methodology and Assumptions
3. Executive Summary
4. Premium Insights
4.1. Porter’s Five Forces Analysis
4.2. Value Chain Analysis
4.3. Top Investment Pockets
4.3.1. Market Attractiveness Analysis By Type
4.3.2. Market Attractiveness Analysis By Application
4.3.3. Market Attractiveness Analysis By Region
4.4. Industry Trends
5. Market Dynamics
5.1. Market Evaluation
5.2. Drivers
5.3. Restraints
5.4. Opportunities
5.5. Challenges
6. Global Fragment Based Drug Discovery Market Analysis and Forecast, By Type
6.1. Segment Overview
6.2. Fragment Screening
6.2.1. Biophysical Techniques
6.2.1.1. DSF Assay
6.2.1.2. Surface Plasmon Resonance
6.2.1.3. Fluorescence Polarization (FP)
6.2.1.4. NMR Spectroscopy
6.2.1.5. X-ray Crystallography
6.2.1.6. Isothermal Titration Calorimetry
6.2.1.7. Mass Spectrometry
6.2.1.8. Other
6.2.2. Non-Biophysical Techniques
6.3. Fragment Optimization
7. Global Fragment Based Drug Discovery Market Analysis and Forecast, By Application
7.1. Segment Overview
7.2. Academic and Research Institutions
7.3. Biopharmaceutical Companies
7.4. Contract Research Organization
8. Global Fragment Based Drug Discovery Market Analysis and Forecast, By Regional Analysis
8.1. Segment Overview
8.2. North America
8.2.1. U.S.
8.2.2. Canada
8.2.3. Mexico
8.3. Europe
8.3.1. Germany
8.3.2. France
8.3.3. U.K.
8.3.4. Italy
8.3.5. Spain
8.4. Asia-Pacific
8.4.1. Japan
8.4.2. China
8.4.3. India
8.5. South America
8.5.1. Brazil
8.6. Middle East and Africa
8.6.1. UAE
8.6.2. South Africa
9. Global Fragment Based Drug Discovery Market-Competitive Landscape
9.1. Overview
9.2. Market Share of Key Players in Global Fragment Based Drug Discovery Market
9.2.1. Global Company Market Share
9.2.2. North America Company Market Share
9.2.3. Europe Company Market Share
9.2.4. APAC Company Market Share
9.3. Competitive Situations and Trends
9.3.1. Product Launches and Developments
9.3.2. Partnerships, Collaborations, and Agreements
9.3.3. Mergers & Acquisitions
9.3.4. Expansions
10. Company Profiles
10.1. Evotec AG
10.1.1. Business Overview
10.1.2. Company Snapshot
10.1.3. Company Market Share Analysis
10.1.4. Company Product Portfolio
10.1.5. Recent Developments
10.1.6. SWOT Analysis
10.2. Charles River Laboratories International
10.2.1. Business Overview
10.2.2. Company Snapshot
10.2.3. Company Market Share Analysis
10.2.4. Company Product Portfolio
10.2.5. Recent Developments
10.2.6. SWOT Analysis
10.3. Crown Bioscience
10.3.1. Business Overview
10.3.2. Company Snapshot
10.3.3. Company Market Share Analysis
10.3.4. Company Product Portfolio
10.3.5. Recent Developments
10.3.6. SWOT Analysis
10.4. Astex Pharmaceuticals
10.4.1. Business Overview
10.4.2. Company Snapshot
10.4.3. Company Market Share Analysis
10.4.4. Company Product Portfolio
10.4.5. Recent Developments
10.4.6. SWOT Analysis
10.5. Sprint Bioscience
10.5.1. Business Overview
10.5.2. Company Snapshot
10.5.3. Company Market Share Analysis
10.5.4. Company Product Portfolio
10.5.5. Recent Developments
10.5.6. SWOT Analysis
10.6. Kinetic Discovery Limited
10.6.1. Business Overview
10.6.2. Company Snapshot
10.6.3. Company Market Share Analysis
10.6.4. Company Product Portfolio
10.6.5. Recent Developments
10.6.6. SWOT Analysis
10.7. Alveus Pharmaceuticals Pvt. Ltd.
10.7.1. Business Overview
10.7.2. Company Snapshot
10.7.3. Company Market Share Analysis
10.7.4. Company Product Portfolio
10.7.5. Recent Developments
10.7.6. SWOT Analysis
List of Table
1. Global Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
2. Global Fragment Screening In Fragment Based Drug Discovery Market, By Region, 2017–2027(USD Billion)
3. Global Fragment Optimization In Fragment Based Drug Discovery Market, By Region, 2017–2027(USD Billion)
4. Global Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
5. Global Academic and Research Institutions Fragment Based Drug Discovery Market, By Region, 2017–2027(USD Billion)
6. Global Biopharmaceutical Companies Fragment Based Drug Discovery Market, By Region, 2017–2027(USD Billion)
7. Global Contract Research Organization Fragment Based Drug Discovery Market, By Region, 2017–2027(USD Billion)
8. Global Fragment Based Drug Discovery Market, By Region, 2017–2027(USD Billion)
9. Global Fragment Based Drug Discovery Market, By North America, 2017–2027(USD Billion)
10. North America Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
11. North America Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
12. U.S. Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
13. U.S. Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
14. Canada Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
15. Canada Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
16. Mexico Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
17. Mexico Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
18. Europe Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
19. Europe Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
20. Germany Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
21. Germany Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
22. France Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
23. France Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
24. U.K. Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
25. U.K. Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
26. Italy Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
27. Italy Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
28. Spain Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
29. Spain Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
30. Asia Pacific Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
31. Asia Pacific Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
32. Japan Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
33. Japan Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
34. China Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
35. China Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
36. India Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
37. India Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
38. South America Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
39. South America Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
40. Brazil Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
41. Brazil Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
42. Middle East and Africa Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
43. Middle East and Africa Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
44. UAE Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
45. UAE Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
46. South Africa Fragment Based Drug Discovery Market, By Type, 2017–2027(USD Billion)
47. South Africa Fragment Based Drug Discovery Market, By Application, 2017–2027(USD Billion)
List of Figures
1. Global Fragment Based Drug Discovery Market Segmentation
2. Fragment Based Drug Discovery Market: Research Methodology
3. Market Size Estimation Methodology: Bottom-Up Approach
4. Market Size Estimation Methodology: Top-Down Approach
5. Data Triangulation
6. Porter’s Five Forces Analysis
7. Value Chain Analysis
8. Global Fragment Based Drug Discovery Market Attractiveness Analysis By Type
9. Global Fragment Based Drug Discovery Market Attractiveness Analysis By Application
10. Global Fragment Based Drug Discovery Market Attractiveness Analysis By Region
11. Global Fragment Based Drug Discovery Market: Dynamics
12. Global Fragment Based Drug Discovery Market Share By Type (2019 & 2027)
13. Global Fragment Based Drug Discovery Market Share by Application (2019 & 2027)
14. Global Fragment Based Drug Discovery Market Share by Regions (2019 & 2027)
15. Global Fragment Based Drug Discovery Market Share by Company (2019)
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